Hormone Replacement Therapy (HRT): Benefits, Myths, and Costs

Hormone Replacement Therapy (HRT): Benefits, Myths, and Costs

Hormone Replacement Therapy (HRT) is a powerful treatment that can improve quality of life for women experiencing hormonal imbalances, particularly due to menopause. While concerns about safety persist, many myths about HRT have been debunked through scientific research. This guide will explore the benefits of HRT, address common misconceptions, and provide an overview of costs.

Benefits of HRT

HRT can significantly improve symptoms related to hormonal decline, offering benefits that include:

Progesterone

• Promotes better sleep quality
• Reduces anxiety and irritability
• Balances the effects of estrogen, reducing the risk of endometrial hyperplasia
• Supports bone health

Estradiol (Estrogen)

• Alleviates hot flashes and night sweats
• Improves vaginal health and reduces dryness
• Supports cognitive function and may reduce the risk of dementia
• Helps maintain bone density, reducing osteoporosis risk
• Improves blood lipid levels 

Testosterone

• Increases muscle mass and strength
• Enhances libido and sexual function
• Supports mood and cognitive function
• Boosts energy levels and reduces fatigue

Debunking Myths About HRT

Myth 1: HRT Causes Cancer

The belief that HRT universally increases cancer risk is misleading. Research has shown that risks depend on the type and formulation of hormones used. For example, bioidentical estradiol combined with micronized progesterone presents a much lower breast cancer risk compared to synthetic hormone combinations (Fournier et al., 2007). Moreover, certain formulations have been associated with a reduced risk of colorectal and endometrial cancer (Baik et al., 2024).

Myth 2: HRT Causes Blood Clots

While oral estrogen can increase clotting markers, studies indicate that it does not significantly increase the actual risk of blood clots when taken appropriately (Lalitkumar et al., 2023). Additionally, transdermal estrogen has been shown to have no impact on clotting risk, making it a safer option for patients with a history of clotting disorders.

Myth 3: HRT Is Unsafe for Women Over 65

New research suggests that continuing HRT beyond age 65 can have health benefits, including reducing mortality risk and lowering the likelihood of dementia and cardiovascular disease (Salpeter et al., 2004; Baik et al., 2024). The decision to continue HRT should be individualized based on patient health and symptom management needs.

Modes of Administration

HRT can be administered in several ways to suit individual preferences and medical needs. The primary methods include:

• Oral (Pills) – Taken by mouth, often as estradiol or progesterone.
• Injectable – Provides a longer-lasting effect, requiring less frequent dosing. 
• Topical (Creams, Gels, Patches) – Applied directly to the skin for gradual hormone absorption.

Mode of administration varies with each hormone and the decision about which to use is made as a collaboration between the patient and the provider, to find what works the best for optimal results for each individual. 

(Note: Pellet therapy is not offered at our clinic due to its inability to provide even hormone levels, increased risk of scarring and infection, and lack of dosage flexibility.)

Cost of HRT

Understanding the financial aspect of HRT is essential for making informed decisions. Below is an overview of the costs at RVA Revive:

• Initial Consultation: $224
• Monthly Hormone Therapy:
  • Single hormone: $189
  • Two hormones: $209
  • Three hormones: $229

These costs include the prescribed hormones and ongoing support from medical professionals to ensure optimal treatment outcomes. Insurance is not accepted. The cost of the monthly program includes both the medication and the expertise of the medical provider.

• Lab Testing: Labs are done approximately every 12 weeks and would incur an additional cost of $99-$199. 

Conclusion

HRT is a valuable tool for managing hormonal imbalances, improving quality of life, and supporting long-term health. With multiple administration options available, women can choose a method that best fits their lifestyle. While myths persist, current scientific research supports the safety and efficacy of properly managed HRT. If you are considering HRT, schedule a consultation at RVA Revive to discuss your specific needs and treatment options.

Contact RVA RevIVe today and discover the transformative benefits tailored just for you!

References

Baik, S. H., Baye, F., & McDonald, C. J. (2024). Use of menopausal hormone therapy beyond age 65 years and its effects on women’s health outcomes. Menopause: The Journal of The Menopause Society, 31(5), 363-371. https://doi.org/10.1097/GME.0000000000002335

Fournier, A., Berrino, F., & Clavel-Chapelon, F. (2007). Unequal risks for breast cancer associated with different hormone replacement therapies: Results from the E3N cohort study. Breast Cancer Research and Treatment, 107(1), 103–111. https://doi.org/10.1007/s10549-007-9523-x

Salpeter, S. R., Walsh, J. M. E., Greyber, E., Ormiston, T. M., & Salpeter, E. E. (2004). Mortality associated with hormone replacement therapy in younger and older women: A meta-analysis. Journal of General Internal Medicine, 19(7), 791-804.

Lalitkumar, P. G. L., Lundström, E., Byström, B., Ujvari, D., Murkes, D., Tani, E., & Söderqvist, G. (2023). Effects of estradiol/micronized progesterone vs. conjugated equine estrogens/medroxyprogesterone acetate on breast cancer gene expression in healthy postmenopausal women. International Journal of Molecular Sciences, 24(4), 4123. https://doi.org/10.3390/ijms24044123